Having both a Stratasys uPrint and an Ultimaker, the actual difference is actually greater than $22k. Yes, the Stratasys can print rafts and supports that dissolve nicely, but everything related to the printer costs WAY more than it needs to. Also, layer height is worse. Your ongoing costs will be astronomical. If you are tied to FDM I would suggest the Ultimakers, Taz, and any of the other brands that have a good community support base.
I did all of that, then switched to resin and haven’t looked back.